#53 Heparin-Induced Thrombocytopenia: 5 Pearls Segment

  Get CME Credit (https://www.acponline.org/cme-moc/online-learning-center/heparin-induced-thrombocytopenia-5-pearls-segment) with ACP! Full Transcript with references and show notes (https://www.coreimpodcast.com/2019/11/13/5-pearls-on-heparin-induced-thrombocytopenia/) Time Stamps 4:30 What is the daily risk of thrombosis if HIT Is left untreated? 5:40 What happens during platelet activation? 07:11 How long does it take for patients to develop for IgG antibodies to Heparin to form? 09:52 Is HIT common? 10:28 Who is at higher risk for HIT? 11:48 Why does low molecular weight heparin have a lower risk for HIT than unfractionated heparin? 15:30 Approach to thrombocytopenia 17:44 How do medications cause thrombocytopenia? 18:38 With medications, what is the time course between medication initiation and thrombocytopenia? 22:20 What is the sensitivity and specificity of anti-PF4 antibody? 23:58 How does the serotonin-release assay (SRA) work? 29:10 What type of anticoagulant do you choose for treating HIT? 31:58 Why is it important to not use warfarin in patients with platelet counts